Association between Brucella melitensis DNA and Brucella sp. Antibodies

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Association between Brucella melitensis DNA and Brucella sp. Antibodies.

Brucella sp. antibodies, despite falling to low levels, can remain measurable after recovery from acute brucellosis (1). Recently, several studies have shown the persistence of Brucella sp. DNA in both chronic brucellosis patients and asymptomatic subjects with a history of brucellosis (2–4, 6). However, to our knowledge, the association between serum antibodies and Brucella sp. DNA has not bee...

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Brucella peritonitis and leucocytoclastic vasculitis due to Brucella melitensis.

Brucellosis is a multisystemic disease that rarely leads to a fatal outcome. While reticuloendothelial system organs are mostly affected, peritonitis and posthepatitic cirrhosis are also complications of brucellosis, though they are very rare. Brucella spp. can also trigger immunological reactions. We report a case of brucellosis with peritonitis, renal failure and leucocytoclastic vasculitis c...

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Antigenic relationship of Brucella ovis and Brucella melitensis.

Immune sera were prepared in rabbits by the injection of living and acetone-killed cells of Brucella ovis and smooth and rough B. melitensis. The use of whole-cell antigens in agglutination and agglutinin-absorption tests revealed little relationship between B. ovis and smooth B. melitensis, although there was extensive cross-agglutination between B. ovis and rough B. melitensis. The use of wat...

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Brucella melitensis prosthetic joint infection

Periprosthetic joint infection (PJI) due to Brucella spp. is rare. We report a case in a 75-year-old man and review 29 additional cases identified in a literature search. The diagnosis of Brucella PJI is challenging, in particular in non-endemic countries. Serological tests prior to joint aspiration or surgical intervention are reasonable. Involvement of infection control and timely information...

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Chronic brucellosis and persistence of Brucella melitensis DNA.

After acute brucellosis infection, symptoms persist in a minority of patients for more than 1 year. Such patients are defined as having chronic brucellosis. Since no objective laboratory methods exist to confirm the presence of chronic disease, these patients suffer delays in both diagnosis and treatment. The aim of the current study was to evaluate the usefulness of quantitative real-time PCR ...

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ژورنال

عنوان ژورنال: Clinical and Vaccine Immunology

سال: 2011

ISSN: 1556-6811,1556-679X

DOI: 10.1128/cvi.00011-11